i've got the same problem, synpase server initialisation failed (see console).
I'm using Gtk radiant 1.4, unchecked the hide extension thing, followed jex's his guide and uninstalled and reïnstalled it multiple times.
I'm using vista, and i think i installed everything right (this time

).
And srry for necroing this topic but if i made a new one, i would probally get scolded for not using the search button ^^
But to make a long story short, what is the reason for the 'synpase server initialisation failed' thing?