Best advice I can tell you is to observe base designs that work and those that dont. Such as, if a newbie builder builds a base, and it fails, you could try and figure out why. Along the same pages, watching how a good builder builds will help you alot.
The 2nd best advice is the learn the maps. 10-1, the original base location is pretty bad in many maps. If you know the map well, you can figure out where to hide an egg(s) the most efficently, and figure out where and when to move the base at the beginning if you need too. Its teh same for humans.
And if you ever decide to be a builder for the Alien team... PLEASE realize that trappers need to point at the target to trap, and that the human team CAN shoot your defense from a distance, so build accordingly.