I dl'ed it from there too, works fine for me, so I doubt that is the problem.
Have you installed synapse,config, defaul_project.proj, and all the other files you need for the setup? I doubt those would be the problem, but it's worth a try.
Also, make sure the file is saved as trem.game, not trem.game.txt (might seem obvious but I have seen some people make this mistake). Notepad and other windows text editors like to automatically append .txt to any file you save unless you tell them otherwise.